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A Simple Fluorescence-based Reporter Assay to Identify Cellular Components Required for Ricin Toxin A Chain (RTA) Trafficking in Yeast
Published on: December 15, 2017
A STUDY OF AN EXTREMELY PURE PREPARATION OF RICIN
1Research Laboratory of the Department of Health, New York, and the Pathological Laboratory of the University of Louisville.
Abstract:
1. By following the method of Osborne, Mendel and Harris, we can obtain an extremely potent toxin from the castor bean. 2. It would appear, as a result of testing this preparation at the end of two and a half years, that the agglutinating function and the toxic function are two distinct properties. 3. This result is also borne out by the behavior under the electric current; either we are dealing with two different substances or else with a single substance with two distinct toxiphore groups, one of which is stable and the other labile.
