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Updated: Jun 19, 2026

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A Mouse Model of Vascularized Heterotopic Spleen Transplantation for Studying Spleen Cell Biology and Transplant Immunity
Published on: June 11, 2019
PANCREATIC TRANSPLANTATIONS IN THE SPLEEN
1Laboratory of the Theory and Practice of Physic, Harvard University, Boston.
The Journal of Experimental Medicine
|October 30, 2009
Abstract:
Pancreatic tissue implanted in the spleen and separated from its original vascular and nervous connections can live and functionate for months. A small nodule of pancreatic tissue composed of acini without demonstrable islands of Langerhans prevented the development of diabetes. Death occurred 187 days after the extirpation of the pancreas.

