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Published on: March 17, 2014
THE OXYGEN CONTENT OF THE BLOOD IN RABBITS INFECTED WITH PNEUMOCOCCUS
1Hospital of The Rockefeller Institute for Medical Research, New York.
Abstract:
In rabbits with a severe pneumococcus bacteremia, the oxygen-combining power of the blood falls progressively up to the time of death. Coincident with this there is an even more marked fall in the oxygen content of the arterial blood. The changes in the blood in infected animals are analogous to those seen when the pneumococcus is grown on blood in vitro. They are due to the conversion of hemoglobin into methemoglobin.
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For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include: