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Updated: Jun 19, 2026

Measuring Nitrite and Nitrate, Metabolites in the Nitric Oxide Pathway, in Biological Materials using the Chemiluminescence Method
Published on: December 25, 2016
THE EXCRETION OF NITROGEN IN FEVER
1Department of Pathological Chemistry of the University of Toronto, Toronto.
Abstract:
The rise of temperature following typhoid vaccination is accompanied by a marked increase in the output of total nitrogen, creatinin, and especially of uric acid. The reaction to tuberculin is slower, but is also accompanied by an increased output of nitrogenous substances, that is, however, less uniform and generally less pronounced. In a case of malaria there was a tendency for the rise of temperature to be accompanied by an increased output of total nitrogen and less uniformly of creatinin; on two days on which the fever was preceded by rigor the output of uric acid was increased.
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