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Updated: Jun 19, 2026

An Experimental Model of Diet-Induced Metabolic Syndrome in Rabbit: Methodological Considerations, Development, and Assessment
Published on: April 20, 2018
THE MORPHOLOGICAL CHANGES IN THE TISSUES OF THE RABBIT AS A RESULT OF REDUCED OXIDATION
H G Martin1, A S Loevenhart, C H Bunting
1Laboratories of Pathology and Pharmacology of the University of Wisconsin, Madison.
Abstract:
Exposure of rabbits to an atmosphere of low oxygen content results in a stimulation of the cardiorespiratory systems, in an extension (hyperplasia) of red bone marrow and probably of a thyroid hyperplasia, with the further production of hydropic and hyaline degeneration in the cells of the parenchymatous organs. An atmosphere of high carbon dioxide and normal oxygen content produces, however, a stimulation of the cardiorespiratory systems, but no marrow extension and, in the concentrations used, but slight hydropic degeneration in the parenchyma of the glandular organs.

