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Related Experiment Video

Updated: Jun 19, 2026

Laparoscopic Technique for Serial Collection of Liver and Mesenteric Lymph Nodes in Macaques

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A CUTANEOUS NEMATODE INFECTION IN MONKEYS.

H F Swift¹, R H Boots, C P Miller

¹Hospital of The Rockefeller Institute for Medical Research.

The Journal of Experimental Medicine

|October 30, 2009

Summary

A novel nematode, Trichosoma cutaneum, infects rhesus monkeys, causing skin lesions and nodules. This parasite exhibits near-perfect parasitism by laying eggs in the epidermis, facilitating host-to-host transmission.

Area of Science:

Veterinary Parasitology
Dermatology
Helminthology

Background:

Nematode infections in non-human primates can cause various dermatological manifestations.
Understanding parasite life cycles and host-parasite interactions is crucial for disease management.

Purpose of the Study:

To describe a newly identified nematode infection in Macacus rhesus monkeys.
To characterize the pathological effects and host immune response to the nematode.
To elucidate the unique reproductive strategy of the parasite.

Main Methods:

Macroscopic and microscopic examination of skin lesions and subcutaneous nodules.
Histopathological analysis of tissue reactions to nematode presence.
Observation of parasite morphology and location within host tissues.

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Published on: December 23, 2016

Main Results:

Infection by a nematode, provisionally named Trichosoma cutaneum, resulted in skin lesions, subcutaneous nodules, joint edema, and blisters on palms and soles.
Larval and adult male nematode forms were found in subcutaneous nodules, eliciting a granulomatous inflammatory response.
Adult female nematodes burrowed into the epidermis, creating blisters for egg deposition, a novel finding for this nematode species.

Conclusions:

Trichosoma cutaneum demonstrates a highly adapted parasitic strategy, laying eggs in the epidermis with minimal host detriment.
This represents the first documented instance of a nematode species laying eggs within the epidermis.
The observed parasitism is considered ideal for nematode species continuation and transmission.