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Updated: Jun 19, 2026

A Non-invasive and Technically Non-intensive Method for Induction and Phenotyping of Experimental Bacterial Pneumonia in Mice
Published on: September 28, 2016
THE LOSS OF CIRCULATING ERYTHROCYTES IN CERTAIN TYPES OF EXPERIMENTAL PNEUMONIA
1Physiological and Bacteriological Laboratories of the University of Wisconsin, Madison.
Abstract:
Erythrocyte counts, blood volume, hemoglobin, and hematocrit determinations on a series of dogs suffering from experimental pneumonia induced by the tracheal insufflation of Bacillus bronchiseplicus and Bacillus mucosus capsulatus indicate that in this condition there is an actual loss of circulating erythrocytes, without compensatory regeneration. Postmortem examination of the organs of these animals revealed red cells in various stages of degeneration in the capillaries and tissue spaces of the lungs, liver, spleen, and intestinal walls.
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