Related Experiment Video
Updated: Jun 19, 2026

Opsonophagocytic Killing Assay to Assess Immunological Responses Against Bacterial Pathogens
Published on: April 5, 2019
IMMUNOLOGICAL RELATIONSHIPS OF CELL CONSTITUENTS OF PNEUMOCOCCUS.
1Hospital of The Rockefeller Institute for Medical Research.
Pneumococcus protein analysis reveals it is a nucleoprotein and mucoid, distinct from soluble substances. This protein demonstrates species specificity, unlike the type specificity of soluble substances.
Area of Science:
- Microbiology
- Biochemistry
Background:
- Pneumococci are bacteria known to cause various infections.
- Understanding the chemical composition of bacterial components is crucial for developing targeted treatments.
Purpose of the Study:
- To chemically characterize the protein component of pneumococci.
- To differentiate the specificity of pneumococcal protein from its soluble specific substance.
Main Methods:
- Precipitation of pneumococcal protein using acetic acid.
- Analysis of chemical reactions of the precipitated protein.
- Comparison of specificity between pneumococcal protein and soluble specific substance.
Main Results:
- The precipitated pneumococcal protein exhibits chemical characteristics of both nucleoprotein and mucoid.
- The pneumococcal protein displays species specificity.
- The non-protein soluble specific substance of pneumococci shows type specificity.
Conclusions:
- The protein isolated from pneumococci is chemically distinct from the soluble specific substance.
- The observed specificity differences suggest distinct biological roles for the protein and soluble substance.
More Related Videos
09:12Characterization of Inflammatory Responses During Intranasal Colonization with Streptococcus pneumoniae
Published on: January 17, 2014
12:21A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness
Published on: September 28, 2022
Related Concept Videos
Atypical Pneumonia
Pneumonia I: Introduction
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Cross-reactivity
Bacterial Meningitis II: Pathophysiology
Pneumonia III: Complications and Assessment