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Characterization of In Vitro Differentiation of Human Primary Keratinocytes by RNA-Seq Analysis
Published on: May 16, 2020
THE DIFFERENTIATION AND KERATINIZATION OF EPITHELIUM IN VITRO
1Laboratories of The Rockefeller Institute for Medical Research and the Institute for General Pathology of the University of Copenhagen, Copenhagen, Denmark.
Abstract:
The organization, or, according to Drew, differentiation, of epithelial cells grown in vitro is not due to a specific influence of the associated connective tissue. It occurs in all old pure cultures of epithelium, when the tissue fragment becomes thick and suffers from lack of oxygen and nourishment. Under the same circumstances, keratinization occurs in cultures of epithelium.
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