Related Experiment Video
Updated: Jun 19, 2026

Establishment and Characterization of UTI and CAUTI in a Mouse Model
Published on: June 23, 2015
SPECIFIC INFECTIOUS CYSTITIS AND PYELONEPHRITIS OF COWS
1Department of Animal Pathology of The Rockefeller Institute for Medical Research, Princeton, N. J.
A urinary tract infection caused by diphtheroids was identified in dairy cows. This condition commonly presents with bloody urine and involves the bladder, ureters, and kidneys.
Area of Science:
- Veterinary Medicine
- Bacteriology
- Animal Pathology
Background:
- Diphtheroid infections can affect various animal species.
- Urinary tract infections (UTIs) in cattle can lead to significant economic losses in dairy herds.
- Understanding the specific pathogens and their impact on bovine urinary systems is crucial for effective treatment and prevention.
Purpose of the Study:
- To identify and characterize a specific urinary tract infection in dairy cows.
- To investigate the causative agent, a diphtheroid bacterium.
- To describe the pathological findings associated with this infection in the bovine urinary system.
Main Methods:
- Clinical examination of affected cows from three dairy herds.
- Gross pathological examination of the urinary tract, including bladder, ureters, and kidneys.
- Microscopic examination of urinary sediment and kidney tissues for the presence of bacilli.
Main Results:
- A distinct urinary tract infection associated with diphtheroids was observed in dairy cows.
- The most common clinical sign was the frequent passage of turbid or blood-stained urine.
- Pathological findings included thickened bladder walls, swollen and reddened mucosa, exudate, and involvement of ureters and kidneys. Diphtheroid bacilli were abundant in urinary sediment and kidney pelves.
Conclusions:
- Diphtheroids can cause specific urinary tract infections in dairy cattle.
- The infection characteristically affects the bladder and can extend to the ureters and kidneys.
- Prompt identification and understanding of this condition are necessary for managing bovine urinary health.
Related Concept Videos
Acute Pyelonephritis I: Introduction
Acute Pyelonephritis II: Diagnostic Studies and Management
Urinary Tract Infection II: Pathophysiology
Urinary Tract Infection I: Introduction
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Urine Studies II: Urine Culture and Sensitivity Test

