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Updated: Jun 19, 2026

Positron Emission Tomography Using 64-Copper as a Tracer for the Study of Copper-Related Disorders
Published on: April 28, 2023
A CHEMICAL AND PATHOLOGIC STUDY OF THE EFFECTS OF COPPER ON THE LIVER
1Departments of Industrial Hygiene and Pathology, College of Physicians and Surgeons, Columbia University, New York.
Abstract:
FROM THE ABOVE STUDIES THE FOLLOWING CONCLUSIONS HAVE BEEN REACHED: 1. That copper or its compounds used does not cause the deposition of pigment in the livers of rabbits, guinea pigs or rats. Neither does it produce a cirrhosis in these animals. 2. That spontaneous deposition of pigment occurs frequently in the livers of normal rabbits on the usual laboratory diet. 3. That the feeding of a diet of carrots exclusively will produce pigment deposition in the livers of rabbits, in every way identical with that ascribed to copper. 4. That the pigment deposited in the livers of rabbits is probably of exogenous origin.
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