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THE SURVIVAL OF YELLOW FEVER VIRUS IN CULTURES

P A Lewis1

  • 1Yellow Fever Laboratory of the International Health Division, Rockefeller Foundation, Bahia, Brazil.

The Journal of Experimental Medicine
|October 30, 2009
PubMed

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Yellow Fever

Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...