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Published on: June 11, 2009
THE ETIOLOGY OF INFECTIOUS DIARRHEA (WINTER SCOURS) IN CATTLE.
1Department of Animal Pathology of The Rockefeller Institute for Medical Research, Princeton, N. J.
The Journal of Experimental Medicine
|October 30, 2009
Summary
A novel bacterial disease in cows causes severe diarrhea with bloody feces. Research identified Vibrios as the causative agent, successfully inducing similar symptoms in calves through experimental infection.
Area of Science:
- Veterinary Medicine
- Microbiology
- Animal Pathology
Background:
- A severe diarrheal disease affecting cows, characterized by dark, bloody feces and intestinal inflammation, was observed.
- Key pathological findings included catarrhal inflammation of the small intestine and liver degeneration.
Purpose of the Study:
- To identify the causative agent of the described bovine diarrheal disease.
- To experimentally reproduce the disease in calves to confirm the etiology.
Main Methods:
- Feces from naturally infected cows were administered to calves to induce disease.
- Vibrios were isolated from the intestinal tracts of affected calves.
- Pure cultures of isolated Vibrios were fed to healthy calves to assess pathogenicity.
Main Results:
- Calves fed feces from affected cows developed a milder form of the disease with similar enteritis.
- Vibrios were successfully cultivated from experimentally infected calves.
- Oral administration of pure Vibrio cultures induced diarrhea and enteritis in some calves, consistent with the natural disease.
Conclusions:
- Vibrios are implicated as the causative agents of this specific bovine diarrheal disease.
- Experimental reproduction of the disease supports the role of Vibrios in bovine enteritis.
- Further investigation into Vibrio strains and their pathogenicity in cattle is warranted.
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