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Updated: Jun 19, 2026

Synthesis, Characterization, and Application of Superparamagnetic Iron Oxide Nanoprobes for Extrapulmonary Tuberculosis Detection
Published on: February 16, 2020
THE ACCUMULATION OF IRON IN TUBERCULOUS AREAS
1Department of Pathology, Harvard University Medical School, Boston.
Abstract:
Repeated daily intravenous injections of ferric chloride solution are followed by an accumulation of iron in tuberculous areas of lungs. The iron accumulates in the caseous areas of tubercles and is demonstrable by the Prussian blue reaction. Quantitative determinations corroborate these results and show that the iron content of lung tissue in tuberculous animals injected with ferric chloride exceeds that in normal animals injected with this salt, as well as that in non-injected tuberculous animals.
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