Related Experiment Video
Updated: Jun 19, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
SERUM SICKNESS IN RABBITS : I. MANIFESTATIONS OF SERUM SICKNESS
1Department of Bacteriology and Hygiene, St. Louis University School of Medicine, St. Louis.
Abstract:
1. The injection of a single large dose of normal horse serum into rabbits results in the appearance 3 to 8 days later of erythematous and edematous reactions on the ears in 68.9 per cent of the animals. 2. The injections may be given by any of several routes and reactions appear when the site of injection is definitely distant from the ears. 3. Injections of various antisera into rabbits cause the appearance of similar reactions. 4. These reactions can be considered as manifestations of serum sickness in rabbits.
More Related Videos
Related Concept Videos
Hypersensitivity Reactions: Immune-Complex Reactions
Antibody Structure
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Nephrotic Syndrome I : Introduction
Rabies
Humoral Immune Responses
Endocarditis II: Clinical Features of Infective Endocarditis

