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Updated: Jun 19, 2026
Characterization of Thymus-dependent and Thymus-independent Immunoglobulin Isotype Responses in Mice Using Enzyme-linked Immunosorbent Assay
Published on: September 7, 2018
PROPERTIES OF THE TYPE SPECIFIC PROTEINS OF ANTIPNEUMOCOCCUS SERA : I. THE MOUSE PROTECTIVE VALUE OF TYPE I SERA WITH
1Hospital of The Rockefeller Institute for Medical Research.
Abstract:
The ability to carry out with some measure of precision mouse protection tests for the estimation of potency of antipneumococcus sera has made possible the correlation of the protective potency with the amount of specifically precipitable protein. With antipneumococcus rabbit sera these protective ratios are relatively constant and higher than those with immune horse serum. Type I antipneumococcus horse sera, on the other hand, show no such constancy but fall into two groups; and there is as yet no simple method for determining to which group a serum belongs.
