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Published on: December 23, 2016
CANINE DISTEMPER IN THE RHESUS MONKEY (MACACA MULATTA).
G Dalldorf1, M Douglass, H E Robinson
1Laboratories of Grasslands Hospital, Valhalla, New York.
The Journal of Experimental Medicine
|October 30, 2009
Summary
Canine distemper virus successfully infected rhesus monkeys. The resulting illness closely mimicked the symptoms observed in infected dogs, indicating a shared disease pathology.
Area of Science:
- Veterinary Virology
- Primate Models
- Infectious Diseases
Background:
- Canine distemper is a highly contagious viral illness affecting domestic dogs.
- Understanding the susceptibility of non-canine species is crucial for disease control and research.
Purpose of the Study:
- To investigate the transmissibility of canine distemper to rhesus monkeys.
- To compare the clinical manifestations of canine distemper in rhesus monkeys with those in dogs.
Main Methods:
- Experimental inoculation of rhesus monkeys with canine distemper virus.
- Observation and documentation of clinical signs and disease progression.
- Comparative analysis of disease features between species.
Main Results:
- Canine distemper was successfully transmitted to rhesus monkeys through various methods.
- The clinical presentation in rhesus monkeys was highly similar, if not identical, to that seen in dogs with distemper.
Conclusions:
- Rhesus monkeys serve as a viable model for studying canine distemper virus.
- The findings highlight the potential for cross-species disease transmission and shared pathogenesis.
