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Updated: Jun 19, 2026

Non-surgical Intratracheal Instillation of Mice with Analysis of Lungs and Lung Draining Lymph Nodes by Flow Cytometry
Published on: May 2, 2011
THE LYMPHATIC PATHWAY FROM THE NOSE AND PHARYNX : THE DISSEMINATION OF NASALLY INSTILLED VACCINIA VIRUS
1Department of Physiology, The Harvard School of Public Health, and the Department of Bacteriology, The Harvard Medical School, Boston.
Abstract:
Vaccinia virus dropped into the nose of a susceptible animal does not appear in cervical lymph in less than 12 hours. After 12 hours, and thereafter continuously for 7 days, a stream of virus is entering the blood through the cervical lymph ducts. Virus passes through the lymph nodes. Virus is fixed by the lymphocytes, and the significance of this is discussed.
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