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Related Concept Videos

Structural Organization of the Human Body: An Overview01:18

Structural Organization of the Human Body: An Overview

It is convenient to consider the body's structures in terms of fundamental levels of organization that increase in complexity: subatomic particles, atoms, molecules, organelles, cells, tissues, organs, organ systems, and organisms.
To study the chemical level of organization, scientists consider the simplest building blocks of matter: subatomic particles, atoms, and molecules. All matter in the universe is composed of one or more unique pure substances called elements, familiar examples of...
Overview of Anatomy and Physiology01:24

Overview of Anatomy and Physiology

Human anatomy is the scientific study of the body's structures. Some of these structures are very small and can only be observed and analyzed with the assistance of a microscope. Other larger structures can readily be seen, manipulated, measured, and weighed. The word "anatomy" comes from a Greek root that means "to cut apart." Human anatomy was first studied by observing the body's exterior and the wounds of soldiers and other injuries. Later, physicians were allowed to dissect the bodies of...
Mass and Weight01:19

Mass and Weight

Mass and weight are often used interchangeably in everyday conversation. For example,  medical records often show our weight in kilograms, but never in the correct units of newtons. In physics, however, there is an important distinction. Weight is the pull of the Earth on an object. It depends on the distance from the center of the Earth. Weight dramatically varies if we leave the Earth's surface, unlike mass, which does not vary with location. On the Moon, for example, the acceleration due to...
Mass and Weight01:19

Mass and Weight

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Levels of Organization01:09

Levels of Organization

Biological organization is the classification of biological structures, ranging from atoms at the bottom of the hierarchy to the Earth's biosphere. Each level of the hierarchy represents an increase in complexity that builds upon the previous level.Molecules Are Composed of Atoms, and Biomolecules Are Assembled from Molecules:The most basic levels include atoms, molecules, and biomolecules. Atoms, the smallest unit of ordinary matter, are composed of a nucleus and electrons. Molecules comprise...
Major Organs of the Digestive System01:19

Major Organs of the Digestive System

The digestive system is responsible for the ingestion of food, secretion of enzymes, mixing and digesting food, absorption of the nutrients and defecation. The human digestive system consists of two major parts: the gastrointestinal tract and the accessory digestive organs.
Gastrointestinal tract:

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Related Experiment Video

Updated: Jun 19, 2026

Sampling Strategies and Processing of Biobank Tissue Samples from Porcine Biomedical Models
05:07

Sampling Strategies and Processing of Biobank Tissue Samples from Porcine Biomedical Models

Published on: March 6, 2018

ORGAN WORK AND ORGAN WEIGHT.

F Walter1, T Addis

  • 1Department of Medicine, Stanford University Medical School, San Francisco.

The Journal of Experimental Medicine
|October 30, 2009
PubMed
Summary

Organ weights like the heart, kidneys, and liver in albino rats are primarily influenced by the work these organs perform. Diet and metabolism significantly impact kidney and liver protein weight, but not heart weight.

Area of Science:

  • Physiology
  • Comparative Anatomy
  • Nutritional Science

Background:

  • Organ growth relative to body weight follows predictable patterns in albino rats.
  • Understanding organ weight regulation is crucial for interpreting physiological changes.

Purpose of the Study:

  • To establish growth ratios for heart, kidneys, and liver relative to body weight in albino rats.
  • To investigate the influence of diet, metabolism, and body composition on organ weights.
  • To test the hypothesis that organ weight changes are driven by organ workload.

Main Methods:

  • Analysis of organ weights from 1591 albino rats under controlled conditions.
  • Experimental manipulation of diet (protein content) and metabolic rate (thyroidectomy, thyroxin, dinitrophenol).

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  • Comparison of organ weights adjusted for body weight, fat, and water content.

    • Main Results:

    • Heart, kidney, and liver protein weights correlate with dietary protein and metabolic rate.
    • Heart weight is independent of diet but responsive to metabolic rate changes.
    • Kidney and liver protein weights generally change in parallel, influenced by workload and diet.

    Conclusions:

    • Organ weight regulation post-weaning is strongly linked to the functional demands placed on the heart, kidneys, and liver.
    • Dietary protein and metabolic state are key modulators of kidney and liver protein mass.
    • Body composition changes necessitate careful consideration when assessing organ weight adjustments.