Related Experiment Video
Updated: Jun 19, 2026

An Optimized Hemagglutination Inhibition (HI) Assay to Quantify Influenza-specific Antibody Titers
Published on: December 1, 2017
CHEMICAL STUDIES ON BACTERIAL AGGLUTINATION : V. AGGLUTININ AND PRECIPITIN CONTENT OF ANTISERA TO HAEMOPHILUS
H E Alexander1, M Heidelberger
1Departments of Pediatrics and Medicine, College of Physicians and Surgeons, Columbia University, and the Presbyterian Hospital, New York.
Abstract:
1. The quantitative, absolute methods of agglutinin and precipitin analysis previously developed for antipneumococcus sera have been shown to be applicable to horse and rabbit anti-influenza type B sera and plasmas. 2. With the aid of these methods and improved immunization schedules the antibody content of the rabbit sera has been increased five to ten times. 3. The method recommended for the purification of rabbit antipneumococcus antibody has also been found applicable to rabbit anti-influenza type B sera.
Related Concept Videos
Blood Typing
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target antigens A,...
Immunoprecipitation
Chromatin Immunoprecipitation
Chromatin immunoprecipitation, also known as ChIP, is used to study protein-DNA or...
Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...

