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Updated: Jun 19, 2026

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1
Published on: August 24, 2015
THE THERMAL INACTIVATION TIME AT 41.5 degrees C. OF THREE STRAINS OF HERPES SIMPLEX VIRUS
R A Boak1, C M Carpenter, S L Warren
1Division of Radiology, Department of Medicine of the University of Rochester School of Medicine and Dentistry, Rochester, New York.
Abstract:
1. The thermal inactivation time at 41.5 degrees C. of the H. F. and Frank strains of herpes simplex virus, under the conditions described, was 80 hours. 2. A strain of herpes virus recently recovered from a patient treated with a physically induced fever had a thermal inactivation time of 50 hours at 41.5 degrees C. 3. The neurotropic factor of the H. F. and Frank strains of virus was more resistant to a temperature of 41.5 degrees C. than the dermotropic factor. There was little difference in the thermostability of these two factors of the Go strain.
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