A COMPARISON OF ERYTHROCYTE SEDIMENTATION RATES AND ELECTROPHORETIC PATTERNS OF NORMAL AND PATHOLOGICAL HUMAN BLOOD

Area of Science:

• Biochemistry
• Hematology
• Clinical Chemistry

Background:

• Erythrocyte sedimentation rate (ESR) and alpha globulin levels are commonly used biomarkers.
• Understanding their relationship in pathological conditions is crucial for diagnosis.

Purpose of the Study:

• To investigate the correlation between alpha globulin levels and erythrocyte sedimentation rates in human blood.
• To assess the diagnostic utility of these markers in inflammation and tissue destruction.

Main Methods:

• Electrophoretic studies were performed on human blood samples.
• Erythrocyte sedimentation rate (ESR) measurements were conducted.
• Alpha globulin levels were quantified using electrophoresis.

Main Results:

• Elevated alpha globulin levels and increased ESR were observed in pathological blood samples.
• A significant positive correlation was found between alpha globulin levels and ESR.
• This correlation was comparable to the correlation between ESR and fibrinogen levels.

Conclusions:

• Alpha globulin levels and ESR are reliable indicators of inflammation and tissue destruction.
• The combined assessment of alpha globulin and ESR offers a valuable diagnostic approach.
• These markers can be used to monitor disease progression and treatment efficacy.