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Related Concept Videos

Viral Structure00:56

Viral Structure

Viruses are extraordinarily diverse in shape and size, but they all have several structural features in common. All viruses have a core that contains a DNA- or RNA-based genome. The core is surrounded by a protective coat of proteins called the capsid. The capsid is composed of subunits called capsomeres. The capsid and genome-containing core are together known as the nucleocapsid.
Size and Structure of Viral Genomes01:26

Size and Structure of Viral Genomes

Viral genomes exhibit remarkable diversity in size, structure, and composition, influencing their replication strategies and interactions with host cells. These genomes consist of either DNA or RNA and may be linear or circular. Additionally, they can be single-stranded or double-stranded, with each configuration affecting how the virus propagates within a host. RNA viruses, for instance, generally have smaller genomes than DNA viruses, a factor that contributes to their high mutation rates and...
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Introduction to Virus01:28

Introduction to Virus

Viruses are unique biological entities that blur the boundary between living and non-living systems. Although they lack cellular structure and metabolic processes, they can exhibit characteristics of life when infecting a host. Their defining feature is a nucleic acid core, composed of either DNA or RNA, encapsulated within a protein coat called a capsid. This simple structure allows them to invade host cells and use their machinery for replication efficiently.Viral Structure and...
Lytic Cycle of Bacteriophages01:30

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Bacteriophages, also known as phages, are specialized viruses that infect bacteria. A key characteristic of phages is their distinctive “head-tail” morphology. A phage begins the infection process (i.e., lytic cycle) by attaching to the outside of a bacterial cell. Attachment is accomplished via proteins in the phage tail that bind to specific receptor proteins on the outer surface of the bacterium. The tail injects the phage’s DNA genome into the bacterial cytoplasm. In the lytic replication...
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Viruses with RNA Genomes

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Related Experiment Video

Updated: Jun 19, 2026

Open-source Single-particle Analysis for Super-resolution Microscopy with VirusMapper
07:38

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Published on: April 9, 2017

MORPHOLOGICAL STRUCTURE OF THE VIRUS OF VACCINIA.

R H Green1, T F Anderson, J E Smadel

  • 1Hospital of The Rockefeller Institute for Medical Research, New York, and the Research Laboratory of the RCA Manufacturing Company, Camden, New Jersey.

The Journal of Experimental Medicine
|October 30, 2009
PubMed
Summary

Electron microscopy reveals consistent morphology in vaccinia virus elementary bodies. These virus particles possess an internal structure and an outer limiting membrane, offering insights into viral organization.

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Last Updated: Jun 19, 2026

Open-source Single-particle Analysis for Super-resolution Microscopy with VirusMapper
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Published on: April 9, 2017

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1
12:00

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Published on: April 8, 2009

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 3
07:35

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 3

Published on: April 13, 2009

Area of Science:

  • Virology
  • Microscopy
  • Cell Biology

Background:

  • Vaccinia virus is a significant subject in virology research.
  • Understanding viral morphology is crucial for comprehending infection mechanisms.

Purpose of the Study:

  • To investigate the detailed morphology of the vaccinia virus elementary body.
  • To identify structuralRegularities and key features of the virus particles.

Main Methods:

  • Utilized electron microscopy to capture high-resolution images of vaccinia virus.
  • Analyzed pictorial data to assess viral particle morphology.

Main Results:

  • Observed a high degree of regularity in the morphology of vaccinia virus elementary bodies.
  • Identified distinct internal structures within the virus particles.
  • Detected the presence of a limiting membrane surrounding the virus particles.

Conclusions:

  • The vaccinia virus elementary body exhibits a highly organized and regular structure.
  • The internal complexity and limiting membrane suggest sophisticated viral architecture.