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Updated: Jun 19, 2026

In Vivo Imaging Systems (IVIS) Detection of a Neuro-Invasive Encephalitic Virus
Published on: December 2, 2012
VENEZUELAN EQUINE ENCEPHALOMYELITIS IN MAN
J Casals1, E C Curnen, L Thomas
1Laboratories of The Rockefeller Institute for Medical Research and the United States Navy Research Unit at the Hospital of The Rockefeller Institute for Medical Research.
Abstract:
A filterable agent was isolated from the blood and from washings of the upper respiratory passages of a young laboratory worker during a mild, acute, febrile illness. This agent was identified as a strain of Venezuelan equine encephalomyelitis virus. Circulating specific complement-fixing and neutralizing antibodies not present in sera withdrawn during the acute phase of illness were demonstrated in sera obtained during convalescence. A fellow laboratory worker who became similarly ill simultaneously also developed during convalescence specific circulating antibodies not present prior to illness.
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