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Induction of Drug-Induced, Autoimmune Hepatitis in BALB/c Mice for the Study of Its Pathogenic Mechanisms
Published on: May 29, 2020
IMMUNITY IN EXPERIMENTALLY INDUCED INFECTIOUS HEPATITIS
1Section of Preventive Medicine, Yale University School of Medicine, New Haven.
Abstract:
1. 9 human volunteers, convalescent from infectious hepatitis experimentally induced by a strain of virus employed in this laboratory, were resistant when reinoculated with the same strain of virus, 6 to 9 months later. 2. 8 out of 12 previously healthy control subjects developed infectious hepatitis with jaundice following administration of this same material. 3. The demonstration of homologous immunity produced by this strain of virus is in agreement with the demonstration by others of homologous immunity produced by another strain of infectious hepatitis virus.
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