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TOLERANCE TO BACTERIAL PYROGENS : II. ROLE OF THE RETICULO-ENDOTHELIAL SYSTEM.

P B Beeson1,

  • 1Medical Service, Grady Hospital, and the Department of Medicine, Emory University School of Medicine, Atlanta.

The Journal of Experimental Medicine
|October 30, 2009
PubMed
Summary

Tolerance to bacterial pyrogens involves faster clearance from blood, with reticuloendothelial system (R-E) blockade impacting this process. This suggests a mechanism for developing unresponsiveness to pyrogenic substances.

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