Related Experiment Video
Updated: Sep 21, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
Outcome probabilities and life history after surgical mitral commissurotomy: implications for balloon commissurotomy
M S Hickey1, E H Blackstone, J W Kirklin
1Department of Surgery, University of Alabama, Birmingham School of Medicine 35294.
Insights
Surgical mitral commissurotomy offers excellent long-term survival for mitral stenosis patients. Initial closed or percutaneous balloon mitral commissurotomy is recommended, avoiding immediate risks associated with open techniques.
Area of Science:
- Cardiology
- Cardiac Surgery
- Interventional Cardiology
Background:
- Mitral stenosis is a significant valvular heart disease.
- Surgical commissurotomy has been a primary treatment modality.
- Long-term outcomes comparing open and closed techniques require further analysis.
Purpose of the Study:
- To evaluate the long-term survival and outcomes of surgical mitral commissurotomy.
- To compare the efficacy and risks of open versus closed surgical techniques.
- To identify risk factors for adverse outcomes after mitral commissurotomy.
Main Methods:
- Retrospective analysis of 339 patients with mitral stenosis undergoing surgical commissurotomy (103 closed, 236 open) between 1967 and 1988.
- Assessment of overall survival rates at various time points (1 month, 1, 5, 10, 20 years).
- Analysis of risk factors for re-intervention, thromboembolism, functional status, and mitral incompetence.
Main Results:
- Overall survival rates at 20 years were 59%.
- Surgical technique (open vs. closed) was not a significant risk factor for survival, re-intervention, or thromboembolism.
- Older age, black race, higher pulmonary vascular resistance, calcification, left ventricular enlargement, and post-commissurotomy mitral incompetence were identified as risk factors.
- Mitral valve replacement was not required within 20 years for 47% of patients.
Conclusions:
- Surgical closed or percutaneous balloon mitral commissurotomy is likely the preferred initial therapy for most mitral stenosis patients.
- The study provides equations to predict and compare outcomes of percutaneous balloon commissurotomy, surgical commissurotomy, and mitral valve replacement.
- Despite potential for mitral incompetence and future valve replacement, initial commissurotomy offers favorable long-term results.
Abstract:
From 1967 to 1988, 339 patients with mitral stenosis underwent surgical commissurotomy, 103 with a closed and 236 with an open technique. The 1 month and 1, 5, 10 and 20 year overall survival rate was 99.7%, 99%, 95%, 87% and 59%, respectively, and the technique (open versus closed) was not a risk factor. Technique was also not a risk factor for a second mitral commissurotomy, subsequent mitral valve replacement, thromboembolism or poor functional status. Risk factors were older age at commissurotomy, black race, higher pulmonary vascular resistance, mitral leaflet calcification, left ventricular enlargement and postcommissurotomy mitral incompetence. The closed technique was a risk factor for mitral incompetence immediately after commissurotomy, but important incompetence developed in only 2 of the 103 patients undergoing closed commissurotomy. Mitral valve replacement was not required within 10 years in 78% of patients and within 20 years in 47%. Despite some increased prevalence of postcommissurotomy mitral incompetence and particularly in view of the considerable long-term likelihood of mitral valve replacement, initial therapy for most patients with mitral stenosis should probably be surgical closed (or percutaneous balloon) mitral commissurotomy. The equations developed in the present study can be used to predict and compare outcome probability after percutaneous balloon commissurotomy with that after surgical commissurotomy and to compare these with outcome probability after mitral valve replacement.
Related Concept Videos
Mitral Valve Prolapse I: Introduction
Mitral Valve Prolapse II: Assessment and Management
Mitral Regurgitation III: Medical Management
Mitral Regurgitation IV: Nursing Management
Mitral Stenosis III: Medical Management
Mitral Stenosis IV: Nursing Management

