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Updated: Jun 19, 2026

Measuring Respiratory Function in Mice Using Unrestrained Whole-body Plethysmography
Published on: August 12, 2014
TEMPERATURE CHARACTERISTICS FOR FREQUENCY OF RESPIRATORY MOVEMENTS IN YOUNG MAMMALS
Abstract:
The internal temperature of 2 day old mice deviates by +0.01 degrees to +3.0 degrees C. from the environmental temperature over a range of 24 degrees . The undeveloped temperature control allows rhythmic activities in this mammalian material to be readily subjected to the analysis afforded by temperature characteristics, and thus makes possible some insight into the physicochemical events controlling vital processes in entire uninjured mammals. The thermal increments and critical temperatures obtained point to a similarity in the controlling system of reactions for both homothermic and poikilothermic organisms. For frequency of respiratory movements the increments 12,340 (19.6 degrees to 35.2 degrees C.); 28,340 or 36,500 (15.5 degrees to 19.6 degrees C.) are most frequently found (thirteen cases). Rarely micro = 8,450, 33,000, or 18,340 (two cases). The last increment is either associated with micro = 36,000 below 20 degrees , or extends unbroken throughout the whole range (one case).
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