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THE ADSORPTION OF GELATIN BY COLLODION MEMBRANES
1Department of Physiology, Yale University, New Haven.
The Journal of General Physiology
|October 30, 2009
Summary
Gelatin adsorption on collodion membranes depends on membrane permeability and solution pH. Salt addition increases adsorption, supporting theories on gelatin particle size influenced by pH and salt.
Area of Science:
- Colloid science
- Physical chemistry
- Materials science
Background:
- Gelatin adsorption is crucial for understanding membrane properties.
- Previous theories by Loeb and Kunitz suggest pH and salt affect gelatin particle size.
Purpose of the Study:
- To experimentally investigate gelatin adsorption by collodion membranes.
- To determine the influence of membrane permeability, pH, and salt concentration on gelatin adsorption.
Main Methods:
- Experimental study of gelatin adsorption at 37°C.
- Utilized collodion membranes with varying permeability.
- Varied gelatin concentration, pH (3.8-6.6), and salt presence.
Main Results:
- High permeability membranes required high gelatin concentrations for maximum adsorption, independent of pH (3.8-4.8).
- Low permeability membranes showed maximum adsorption at lower concentrations, varying with pH (3.8-6.6), lower near the isoelectric point.
- Salt addition increased maximum adsorption, equaling that at the isoelectric point without salt.
Conclusions:
- Results support Loeb and Kunitz's theory on pH and salt effects on gelatin particle size.
- Membrane permeability significantly influences gelatin adsorption dynamics.
- Adsorption behavior is consistent with changes in gelatin particle aggregation state.
