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TEMPERATURE CHARACTERISTICS FOR HEART BEAT FREQUENCY IN MICE
W J Crozier1, G Pincus, B Renshaw
1Laboratory of General Physiology, Harvard University, Cambridge.
The Journal of General Physiology
|October 30, 2009
Summary
This study introduces a new apparatus for simultaneously measuring young mice body temperature and heart rate. The findings reveal distinct temperature characteristics related to heart rate across different temperature ranges.
Area of Science:
- Physiology
- Animal Models
Background:
- Understanding thermoregulation and cardiovascular responses in young mice is crucial for preclinical research.
- Existing methods may not allow for simultaneous, precise measurement of body temperature and heart rate.
Purpose of the Study:
- To describe an apparatus for simultaneous recording of body temperature and heart rate in young mice.
- To characterize the relationship between heart rate and body temperature in a specific mouse strain.
Main Methods:
- Development and utilization of a novel apparatus for simultaneous physiological measurements.
- Recording body temperature and heart rate in young mice across a defined temperature range.
Main Results:
- The apparatus successfully enabled simultaneous measurement of body temperature and heart rate.
- Temperature characteristic values (related to heart rate) were determined: 22,400+/- calories (15-20°C), 16,000+/- calories (20-27°C), and 11,000+/- calories (27-35°C).
Conclusions:
- The described apparatus is effective for simultaneous measurement of body temperature and heart rate in young mice.
- The study provides specific temperature characteristic values for an inbred albino mouse strain, aiding in physiological assessments.
