Related Experiment Video
Updated: Jun 19, 2026

Manganese Oxide Nanoparticle Synthesis by Thermal Decomposition of Manganese(II) Acetylacetonate
Published on: June 18, 2020
THE COMBINATION OF DIVALENT MANGANESE WITH CERTAIN PROTEINS, AMINO ACIDS, AND RELATED COMPOUNDS
1Division of Biochemistry, University of California Medical School, Berkeley.
Abstract:
1. A study of the mode of combination which takes place between certain amino acids, proteins, various carboxylic acids, and certain sulfonic acids and manganous ions to form complexes is reported. 2. Three criteria for complex formation were used: (a) the equilibrium between the substance under test and manganous ions dissolved in aqueous buffered solution and isonitrosoacetophenone dissolved in chloroform; (b) the electrophoretic migration of manganese in the presence of the test substance with varying pH; and (c) anomalous titration. 3. The following classes of substances were found to possess the necessary groupings to form manganese complexes: hydroxy-monocarboxylic acids (lactic, gluconic), dicarboxylic acids (oxalic, malonic), hydroxy-, di- and tricarboxylic acids (citric, tartaric), dicarboxylic amino acids (aspartic, glutamic), certain inorganic acids (phosphoric, sulfuric), certain phosphoric acid-containing compounds (nucleic, glycerophosphoric), certain aromatic enol sulfonic acids (phenolsulfonic, catecholsulfonic), and certain proteins (casein, edestin, gelatin). 4. A correlation between the amount of manganese bound by the several proteins and the free carboxyl and phosphoric acid groups has been made. 5. An explanation based on the residual charge of certain atoms is advanced for the manner in which divalent manganese may be united by the compounds studied.
More Related Videos
04:48Setup of Capillary Electrophoresis-Inductively Coupled Plasma Mass Spectrometry (CE-ICP-MS) for Quantification of Iron Redox Species (Fe(II), Fe(III))
Published on: May 4, 2020
11:04Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
Published on: September 7, 2019
Related Concept Videos
Microbes and Other Elemental Cycles
Essential Minerals for Bone Health
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Metal-Ligand Bonds
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
Cofactors and Coenzymes
Cofactors can be metallic ions or organic molecules called coenzymes. These types of helper...
Cofactors and Coenzymes
Cofactors and Coenzymes