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FURTHER CHEMICAL STUDIES ON BLOOD-AQUEOUS HUMOR DYNAMICS

V E Kinsey1, W M Grant

  • 1Howe Laboratory of Ophthalmology, Harvard Medical School, Boston.

The Journal of General Physiology
|October 30, 2009
PubMed

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...