Related Experiment Video
Updated: Jun 19, 2026

Characterizing Single-Molecule Conformational Changes Under Shear Flow with Fluorescence Microscopy
Published on: January 25, 2020
STUDIES ON THE ANOMALOUS VISCOSITY AND FLOW-BIREFRINGENCE OF PROTEIN SOLUTIONS : I. GENERAL BEHAVIOUR OF PROTEINS
A S Lawrence1, J Needham, S C Shen
1Biochemical Laboratory, University of Cambridge.
Abstract:
1. A coaxial viscosimeter which permits the simultaneous determination of relative and anomalous viscosity and of flow-birefringence is described. Flow-anomaly and flow-birefringence are regarded as characteristic of elongated micelles and molecules. 2. Such methods have been applied to dilute solutions of proteins. The conditions under which the coaxial (Couette) viscosimeter measures the viscosity of the bulk phase and the surface film phase respectively have been investigated and are described. 3. The general behaviour of protein solutions subjected to shear is summarised.
Related Concept Videos
Newtonian Fluid: Problem Solving
A velocity gradient forms within the fluid when a Newtonian fluid is placed between two parallel plates, with...
Viscosity
The SI unit of viscosity is...
Viscosity
Types of Fluids
In contrast, non-Newtonian fluids do not follow Newton's law of viscosity, and their...
Viscosity of Fluid
Problem Solving on Stress and Strain

