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Lichen planus in childhood: report of 100 cases

A J Kanwar1, D De

  • 1Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. ajkanwar1948@gmail.com

Clinical and Experimental Dermatology
|October 31, 2009
PubMed

Insights

This study reports on 100 children with lichen planus (LP), the largest to date. While hepatitis B vaccination is a suspected trigger, few patients in this study received it, suggesting other factors may be involved in childhood LP.

Area of Science:

  • Pediatric Dermatology
  • Immunology

Background:

  • Lichen planus (LP) is rare in children, with limited large-scale research available.
  • Existing literature primarily consists of case reports and small case series.

Purpose of the Study:

  • To present findings from the largest study to date on childhood lichen planus.
  • To characterize the clinical presentation and potential triggers of LP in pediatric patients.

Main Methods:

  • Retrospective analysis of 100 pediatric patients diagnosed with lichen planus.
  • Data collection included patient demographics, age at onset, affected sites, morphology, and vaccination history.

Main Results:

  • The study included 100 children with a mean age of 8.76 years (disease onset at 7.6 years).
  • Lesions most commonly appeared on the legs (54%), with papular morphology being the most frequent (42%).
  • Oral mucosa involvement was observed in 17% and nail involvement in 19% of patients.

Conclusions:

  • Hepatitis B vaccination has been implicated in LP onset, but only 16 patients in this cohort were vaccinated.
  • The low rate of hepatitis B vaccination among affected children suggests a complex etiology for childhood LP.
  • Future increases in childhood LP cases may occur if a causal link with routine hepatitis B vaccination in India is established.
Abstract

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