Related Experiment Video
Updated: Jun 19, 2026

A Rapid and Specific Microplate Assay for the Determination of Intra- and Extracellular Ascorbate in Cultured Cells
Published on: April 11, 2014
Scurvy: forgotten but definitely not gone
Debbie Popovich1, Allison McAlhany, Abimbola O Adewumi
1University of Florida College of Nursing, Gainesville, FL 32610, USA. popovdm@ufl.edu
Abstract:
Scurvy, a disease of vitamin C deficiency, is purportedly rare in the United States yet frequently may be misdiagnosed. Presenting symptoms include bone pain, limping, rashes, or spongy bleeding gingiva. These symptoms mimic many other disorders, which often results in numerous unnecessary, invasive, and expensive procedural investigations. The strongest indication of a scurvy diagnosis is the dramatic response to the administration of vitamin C. This case report demonstrates the complexities involved in determining the cause of one child's symptoms. A thorough nutritional history and a shrewd clinician are essential to the early diagnosis and treatment of scurvy.
Related Concept Videos
Vitamins
Forgetting
Encoding...
Smallpox
Cirrhosis I: Introduction
Cirrhosis II: Pathophysiology
Fatigue
