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Neuropsychological status of elderly patients with diabetes mellitus

Hiroyuki Shimada1, Takami Miki, Akiko Tamura

  • 1Department of Geriatrics and Neurology, Osaka City University Medical School, Japan. h.shimada@med.osaka-cu.ac.jp

Diabetes Research and Clinical Practice
|October 31, 2009
PubMed
Abstract

Insights

Diabetes mellitus is linked to cognitive decline. Many diabetic patients show normal cognition, but a significant portion experience mild cognitive impairment or dementia, highlighting the need for monitoring.

Area of Science:

  • Neurology
  • Endocrinology
  • Geriatrics

Background:

  • Diabetes mellitus (DM) is a known risk factor for Alzheimer's disease (AD).
  • The specific relationship between DM and amnestic mild cognitive impairment (aMCI), marked by memory loss, requires further investigation.

Purpose of the Study:

  • To determine the prevalence of mild cognitive impairment (MCI) in patients with diabetes mellitus.
  • To assess the cognitive status of diabetic patients.

Main Methods:

  • 103 diabetic patients underwent neuropsychological evaluation using the Rivermead Behavioral Memory Test (RBMT) and Mini Mental State Examination (MMSE).
  • Exclusion criteria included severe diabetic complications or cerebrovascular accidents.

Main Results:

  • 71% of diabetic patients had normal cognitive function (MMSE ≥24, RBMT ≥15).
  • 5% were diagnosed with amnestic mild cognitive impairment (aMCI) (MMSE ≥24, RBMT <15).
  • 23% of patients had dementia (MMSE <24), a significantly higher rate than controls (p<0.04). A mild correlation was found between RBMT scores and HbA1c levels.

Conclusions:

  • Elevated blood sugar in diabetic patients may impair memory and other cognitive functions.
  • Regular neuropsychological monitoring is crucial for individuals with diabetes mellitus.

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