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Related Concept Videos

Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Type II Diabetes I: Introduction01:26

Type II Diabetes I: Introduction

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
Diabetes Mellitus: Introduction01:26

Diabetes Mellitus: Introduction

Diabetes mellitus consists of chronic metabolic disorders characterized by persistent hyperglycemia. This elevated blood glucose results from defects in insulin secretion, impaired insulin action, or both. Insulin, produced by pancreatic β-cells, is essential for maintaining glucose homeostasis by facilitating cellular glucose uptake for energy or storage. Disruptions in insulin production or function lead to glucose accumulation in the bloodstream, causing the clinical features and long-term...
Carbohydrate Metabolism01:36

Carbohydrate Metabolism

Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in the...

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Related Experiment Video

Updated: Jun 19, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Obesity and gestational diabetes.

T Sathyapalan1, D Mellor, S L Atkin

  • 1Department of Diabetes, Endocrinology and Metabolism, Hull York Medical School, Hull, UK.

Seminars in Fetal & Neonatal Medicine
|October 31, 2009
PubMed
Summary

Obesity significantly worsens complications for women with gestational diabetes mellitus (GDM). Effective glycaemic control and postpartum follow-up are crucial for managing risks in pregnant individuals with GDM and obesity.

Area of Science:

  • Obstetrics and Gynecology
  • Endocrinology
  • Public Health

Background:

  • Global rise in obesity and gestational diabetes mellitus (GDM) prevalence.
  • GDM affects approximately 7% of pregnancies, characterized by impaired glucose tolerance.
  • Obesity exacerbates maternal and fetal complications in GDM pregnancies.

Purpose of the Study:

  • To discuss the impact of obesity on women with GDM.
  • To review treatment strategies for GDM in obese pregnant individuals.
  • To highlight the importance of long-term risk modification and postpartum care.

Main Methods:

  • Literature review and synthesis of existing research.
  • Analysis of the relationship between obesity, GDM, and pregnancy outcomes.

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Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
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Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes

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  • Discussion of current and potential therapeutic interventions.
  • Main Results:

    • Obesity is a significant risk factor for adverse outcomes in GDM.
    • Good glycaemic control can mitigate some GDM-related complications.
    • Comprehensive management strategies are needed for affected women.

    Conclusions:

    • Obesity poses substantial risks in GDM pregnancies.
    • Effective management requires integrated approaches including glycemic control, treatment options, and long-term follow-up.
    • Postpartum care is essential for modifying long-term health risks.