Pterygia: single-fraction postoperative beta irradiation

Area of Science:

• Ophthalmology
• Radiation Oncology

Background:

• Pterygium is a common ocular condition requiring surgical excision.
• Postoperative management aims to prevent recurrence and maintain visual function.

Purpose of the Study:

• To evaluate the long-term efficacy and safety of strontium-90 (Sr-90) beta irradiation as an adjunct to pterygium excision.

Main Methods:

• Retrospective review of 128 patients (146 eyes) treated between 1982-1988.
• Single postoperative application of Sr-90 delivering 3,000 cGy in one fraction.
• Median follow-up of 13 months.

Main Results:

• Actuarial freedom from relapse was 87%, with all recurrences within 18 months.
• Ultimate disease control rate of 96.3% achieved.
• No serious complications; transient conjunctivitis and photophobia were common.

Conclusions:

• A single Sr-90 application post-pterygium surgery is an effective and safe treatment modality.
• Early recurrences were successfully managed with re-treatment.
• Sr-90 irradiation demonstrates a favorable risk-benefit profile for pterygium management.