Related Experiment Video
Updated: Jun 19, 2026

In Vitro Scratch Assay to Demonstrate Effects of Arsenic on Skin Cell Migration
Published on: February 23, 2019
[Advance on oxidative stress mechanism of arsenic toxicology]
1Department of Radiation Effect, Institute of Radiation Medicine, Shandong Academy of Medical Sciences, Jinan 250062, China.
Abstract:
Inorganic arsenic is one of proven human carcinogens, which there are so far no sound laboratory-based evidences and there are very few reports in the literature regarding arsenic carcinogenic effects in in vivo animal experiment. Because of this lack of adequate evidences, the mechanism for understanding arsenic toxicology remains vague. Recently, many modes of action for arsenic carcinogenesis have been proposed, oxidative stress is one of the stronger theories of arsenic action modes which have a substantial mass of supporting data. Further more, many researchers have pointed out that induction of oxidative stress by methylated metabolites of inorganic arsenics plays an important role in the toxicity and carcinogenicity of arsenics. The role of oxidative stress induced by arsenic in arsenic toxicology was reviewed.
More Related Videos
09:23Removal of Trace Elements by Cupric Oxide Nanoparticles from Uranium In Situ Recovery Bleed Water and Its Effect on Cell Viability
Published on: June 21, 2015
09:33Imaging Approaches to Assessments of Toxicological Oxidative Stress Using Genetically-encoded Fluorogenic Sensors
Published on: February 7, 2018
Related Concept Videos
Bioactivation and Tissue Toxicity
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Anticholinesterase Agents: Poisoning and Treatment
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is slower than the...
Sulfur Assimilation
Aging
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Acid Mine Drainage