Related Experiment Video
Updated: Jun 19, 2026
08:33
Induction and Assessment of Exertional Skeletal Muscle Damage in Humans
Published on: December 11, 2016
[Exercise induced rhabdomyolysis]
Maja Ruzic1, Milotka Fabri, Marta Pobor
1Klinicki centar Vojvodine, Klinika za infektivne bolesti, Novi Sad, Srbija. majaruzic@neobee.net
Vojnosanitetski Pregled
|November 3, 2009
Summary
Excessive muscular activity, a common cause of rhabdomyolysis, can mimic hepatitis. This condition involves muscle breakdown and potential kidney damage, often overlooked in healthy individuals.
Area of Science:
- Medical Science
- Clinical Medicine
- Pathology
Context:
- Rhabdomyolysis is a serious condition involving skeletal muscle breakdown.
- It can lead to acute kidney injury and is characterized by the release of intracellular components.
- This case highlights a diagnostic challenge in a young patient.
Purpose:
- To present a case of rhabdomyolysis.
- To discuss the clinical presentation and diagnostic workup.
- To emphasize the link between strenuous exercise and rhabdomyolysis.
Summary:
- A 19-year-old male presented with symptoms mimicking viral hepatitis, including elevated liver enzymes.
- Further investigations revealed elevated creatine kinase and lactate dehydrogenase, indicative of muscle damage.
- Neurological examination and electromyography suggested neuromyositis, leading to a diagnosis of rhabdomyolysis.
Impact:
- Excessive exercise is a frequently overlooked cause of rhabdomyolysis in healthy individuals.
- Rhabdomyolysis can present with elevated aminotransferases, potentially leading to misdiagnosis as hepatitis.
- Early recognition and diagnosis are crucial to prevent complications like acute renal failure.
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