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Updated: Jun 19, 2026

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
08:22

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

Published on: August 11, 2017

Tissue engineering: biomedical applications.

R Langer1, J P Vacanti, C A Vacanti

  • 1Department of Chemical Engineering, and Division of Health Science & Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139.

Tissue Engineering
|November 3, 2009
PubMed
Summary
This summary is machine-generated.

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This study explores tissue engineering using biodegradable polymer scaffolds seeded with mammalian cells. These cell-polymer constructs are cultivated in vitro before in vivo implantation for tissue regeneration.

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Tissue Engineering

Background:

  • Tissue engineering aims to restore or improve tissue function.
  • Biodegradable polymer scaffolds offer a promising platform for cell growth and tissue formation.
  • In vitro cultivation and in vivo implantation are key stages in tissue engineering.

Purpose of the Study:

  • To present a novel tissue engineering approach using biodegradable polymer scaffolds.
  • To detail methods for in vitro cell cultivation on scaffolds.
  • To examine the in vitro and in vivo applications of this technique for various tissues.

Main Methods:

  • Seeding mammalian cells onto biodegradable polymer scaffolds.
  • In vitro cultivation of cell-polymer constructs under specific bioreactor conditions.

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Experimental Approaches to Tissue Engineering

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Tissue Engineering of a Human 3D in vitro Tumor Test System

Published on: August 6, 2013

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Last Updated: Jun 19, 2026

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
08:22

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

Published on: August 11, 2017

Experimental Approaches to Tissue Engineering
16:41

Experimental Approaches to Tissue Engineering

Published on: August 30, 2007

Tissue Engineering of a Human 3D in vitro Tumor Test System
11:12

Tissue Engineering of a Human 3D in vitro Tumor Test System

Published on: August 6, 2013

  • In vivo implantation of engineered cell-polymer constructs.

    • Main Results:

    • Successful cultivation of mammalian cells on polymer scaffolds.
    • Demonstrated feasibility of in vitro and in vivo applications.
    • Potential for generating diverse tissues including cartilage, tendon, liver, urothelial tissue, intestine, and bone.

    Conclusions:

    • The discussed approach is a viable strategy for tissue engineering.
    • Biodegradable polymer scaffolds facilitate in vitro cell growth and in vivo tissue formation.
    • This method holds promise for regenerating multiple human tissue types.