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Updated: Jun 19, 2026

Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development
Published on: January 26, 2018
Use and abuse of oxytocin for augmentation of labor
Lotta Selin1, Elisabeth Almström, Gunnar Wallin
1Department of Obstetrics and Gynecology, NU Hospital Group, Trollhättan, Sweden. lotta.selin@vgregion.se
Objective:
To investigate the use of oxytocin for augmentation of labor and its relation to labor progress and delivery outcome.
Design And Setting:
A retrospective observational study undertaken in a Swedish hospital during 2000-2001.
Sample:
Singleton pregnancies at > or = 37 weeks of gestation with cephalic presentation and spontaneous onset of labor.
Methods:
Data were collected from 1,263 clinical records. The partogram was used to diagnose labor dystocia (LD).
Main Outcome Measures:
Prevalence of oxytocin administration, LD and operative delivery.
Results:
Oxytocin was administered to 55% of the women (75% of primiparas and 38.1% of multiparas); a majority did not meet LD criteria. LD frequency was 19.8% (32.7% in primiparas and 7.4% in multiparas). Oxytocin was started both 'too early' and 'too late' in relation to the diagnosis of LD. Cesarean section (CS) was performed on 17.1% of primiparous and 2.4% of multiparous oxytocin recipients with LD, compared to 2.3 and 1.5%, respectively, of oxytocin recipients without diagnosed LD.
Conclusions:
Oxytocin augmentation was undertaken in an unstructured manner; some women were inadequately treated and others were treated unnecessarily. Oxytocin recipients with LD underwent operative delivery to a higher extent than oxytocin recipients without LD, suggesting that the main reason for CS was the underlying problem of LD rather than the oxytocin augmentation itself.
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