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[Takayasu's disease in central Tunisia: 27 cases]
N Ghannouchi Jaafoura1, M Khalifa, A Rezgui
1Service de médecine interne et maladies infectieuses, CHU Farhat Hached, 4000 Sousse, Tunisie. neirouz.ghannouchi@rns.tn
Journal Des Maladies Vasculaires
|November 3, 2009
Summary
Takayasu's arteritis in Tunisia primarily affects young females, with subclavian artery involvement being more common than aortic disease. Diagnosis delays are significant, impacting patient outcomes.
Area of Science:
- Rheumatology
- Vascular Medicine
- Epidemiology
Background:
- Takayasu's arteritis is a rare inflammatory condition.
- Limited data exists on its prevalence and characteristics in Tunisia.
- This study addresses the need for local data.
Purpose of the Study:
- To evaluate the clinical and radiological features of Takayasu's arteritis.
- To describe the disease's presentation and progression in central Tunisia.
Main Methods:
- Retrospective study of medical records from 1985-2005.
- Inclusion criteria based on American College of Rheumatology criteria.
- Data collected from three university hospitals in Sousse and Monastir.
Main Results:
- 27 patients identified; 88.9% female, mean age 33.2 years.
- Common presentation: intermittent claudication (81.5%), hypertension (40.7%).
- Most frequent arterial involvement: subclavian artery, aorta (52.3%), renal arteries (36.3%). Stenosis/occlusion constant; aneurysms in 7.4%.
Conclusions:
- Takayasu's arteritis in Tunisia shows no unique epidemiological features.
- Subclavian artery involvement is more frequent than aortic localization.
- Functional difficulties were common during follow-up; mortality was low (3.7%).
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