Related Experiment Video

Updated: Jun 19, 2026

A Rat Carotid Artery Pressure-Controlled Segmental Balloon Injury with Periadventitial Therapeutic Application
06:53

A Rat Carotid Artery Pressure-Controlled Segmental Balloon Injury with Periadventitial Therapeutic Application

Published on: July 9, 2020

Carotid endarterectomy versus carotid angioplasty cui bono

W S Moore1

  • 1Division of Vascular Surgery, David Geffen School of Medicine at UCLA, 200 UCLA Medical Plaza, Room 510-6, Los Angeles, CA 90095-6908, USA. wmoore@mednet.ucla.edu

European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
|November 3, 2009
PubMed

Insights

Carotid endarterectomy (CEA) is currently favored over carotid angioplasty (CAS) for managing carotid bifurcation disease due to better outcomes in stroke, mortality, and cost-effectiveness.

Area of Science:

  • Vascular Surgery
  • Interventional Cardiology
  • Cerebrovascular Disease Management

Background:

  • Carotid bifurcation disease poses a significant risk for stroke.
  • Surgical intervention is often necessary to prevent ischemic events.
  • Carotid endarterectomy (CEA) and carotid angioplasty with stenting (CAS) are primary treatment options.

Purpose of the Study:

  • To compare the efficacy and safety of CEA versus CAS.
  • To evaluate current treatment standards for carotid bifurcation disease.

Main Methods:

  • Retrospective review of published and presented prospective randomized trials.
  • Inclusion of six published trials, one in press, and one undergoing analysis.
  • Consideration of large population-based and registry studies.

Main Results:

  • CEA demonstrates superior outcomes compared to CAS.
  • CEA shows lower stroke morbidity and mortality rates.
  • CEA offers better freedom from recurrence and is more cost-effective.

Conclusions:

  • Carotid endarterectomy (CEA) is the preferred intervention for carotid bifurcation disease.
  • Current evidence supports CEA as the gold standard treatment.
Abstract

Related Concept Videos

Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
Angina IV: Management01:26

Angina IV: Management

IntroductionThe management of angina requires a comprehensive approach that includes pharmacological therapies, medical procedures, and lifestyle modifications.Pharmacological TherapiesAntiplatelet agents, such as aspirin, clopidogrel, prasugrel, and ticagrelor, play a pivotal role in preventing thrombus formation in patients with angina. These medications inhibit platelet aggregation and reduce the likelihood of myocardial infarction and other cardiovascular events.Anticoagulants, including...