Reconstruction following resection of soft-tissue sarcomas at the ankle region in seven patients
Related Experiment Video
Updated: Jun 19, 2026

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies
Published on: July 28, 2020
Akira Saito1, Masayuki Sawaizumi, Tomohiro Imai
1Department of Plastic and Reconstructive Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-10-6, Koto-ward, Tokyo Post-code 135-8550, Japan. megane-31@ima.me-h.ne.jp
Abstract:
The defects following soft-tissue or bone malignancies resection tend to be wide and composite at the region of ankle, and reconstruction of the defects is a difficult task. Between 1982 and 2007, we performed reconstruction for the defects of the ankle region in seven patients. All of the patients underwent free tissue transfer, and the selected methods are different for each case. No perioperative complications have occurred in any patients. All flaps survived completely. Two patients had local recurrence and amputation was carried out. Functional and aesthetical improvement is desirable for reconstruction of the ankle. We consider it important to select reconstructive options based on the size and volume of the defects and tissue deficiency; and free tissue transfer is useful for the reconstruction of the wide and composite defects at the ankle region.