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Updated: Jun 19, 2026

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
Published on: August 9, 2012
An alternative method for determining daily bladder perception
Erim Erdem1, Sinan Karazindiyanoglu, Suleyman Ulger
1Department of Urology, Mersin University School of Medicine, Mersin, Turkey. erdemerim@mersin.edu.tr
Insights
Daily bladder sensations in children do not correlate with cystometry findings. However, repeated daily recordings show strong correlation, suggesting a need for further reliability comparisons between methods for evaluating bladder perception.
Area of Science:
- Urology
- Pediatrics
- Clinical Research
Background:
- Cystometry, a common tool for assessing bladder function, may present unphysiologic conditions.
- Evaluating bladder perception in children requires reliable and non-invasive methods.
Purpose of the Study:
- To investigate a novel tool for evaluating bladder perceptions in children.
- To compare daily voiding chart data with cystometry measurements.
Main Methods:
- 25 children with primary monosymptomatic enuresis (mean age 11) participated.
- Children recorded normal desire (ND) and strong desire (SD) durations daily.
- Cystometry measured volume (ml) and duration (sec) to perceived ND and SD.
Main Results:
- Cystometry showed strong correlation between duration (sec) and volume (ml) for ND/SD.
- Repeated daily recordings (3 times) demonstrated strong intra-subject correlation for ND, SD, and ND/SD.
- No significant correlation was found between daily recorded durations and cystometry-perceived durations for ND or SD.
Conclusions:
- Daily recorded bladder sensations do not correlate with those measured during cystometry.
- The high correlation of repeated daily recordings suggests their potential reliability.
- Further studies are needed to compare the reliability of daily voiding charts versus cystometry for bladder perception assessment.
Objectives:
To avoid the unphysiologic nature of cystometry, we searched a new tool for evaluating bladder perceptions.
Methods:
The study group consisted of 25 (14 girls and 11 boys) primary monosymptomatic enuretic children with a mean age of 11 (range 8-16). Four children were excluded due to neuromuscular dysfunctions of the bladder, which was demonstrated with the help of cystometry. All children filled a voiding chart 3 times daily to record the duration elapsed till normal desire (ND(daily)) and strong desire (SD(daily)). During cystometry, the amounts of infused medium (cystometric ND(ml) and cystometric SD(ml)) and the duration (cystometric ND(sec) and cystometric SD(sec)), till ND and SD were perceived and recorded.
Results:
Mean cystometric ND(ml) was 209.9 +/- 107.2 and ND(sec), 318.1 +/- 135.5, whereas mean cystometric SD(ml) was 273.0 +/- 103.1 and SD(sec), 415.7 +/- 136.8. To evaluate the reliability of elapsed time instead of milliliters, as a parameter, cystometric ND/SD values were calculated and a strong correlation was found between the 2 (ND/SD(sec) = 0.77 +/- 0.19 and ND/SD(ml) = 0.77 +/- 0.19, r = 0.9795, P = .000). Although there was a strong correlation between 3 ND(daily) (r = 0.9576, P = .000), between 3 SD(daily) (r = 0.9706, P = .000), and 3 ND/SD(daily) (r = 0.8706, P = .000), no significant correlation was determined between mean ND(daily) and cystometric ND(sec) (r = 0.3410, P = .2032), and also between mean SD(daily) and cystometric SD(sec) (r = 0.2740, P = .2402).
Conclusions:
Daily durations of sensations do not correlate with those perceived during cystometry. However, as the results of 3 consecutive daily recordings have a strong correlation, comparison of the reliability of these methods is still needed.
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