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Updated: Jun 19, 2026

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats
Published on: September 19, 2025
Respiratory motion correction for image-guided cardiac interventions using 3-D echocardiography
A P King1, C Jansen, K S Rhode
1Division of Imaging Sciences, King's College, 4th Floor Lambeth Wing, St. Thomas' Hospital, London SE1 7EH, UK. andrew.king@kcl.ac.uk
A new method using 3-D echocardiography (echo) and a respiratory motion model improves motion correction for cardiac interventions. This model-based technique is more accurate and computationally efficient than echo-only methods.
Area of Science:
- Medical Imaging
- Cardiovascular Interventions
- Image-Guided Therapy
Background:
- Respiratory motion significantly impacts the accuracy of roadmaps in image-guided cardiac interventions.
- Accurate respiratory motion correction is crucial for precise navigation during these procedures.
Purpose of the Study:
- To investigate the efficacy of 3-D echocardiography (echo) data for respiratory motion correction of roadmaps.
- To compare a novel model-based technique with an echo-only technique for motion correction accuracy and robustness.
Main Methods:
- Developed two techniques: one using echo-echo registration alone, and a second combining echo-echo registration with a cardiac respiratory motion model.
- Tracked and calibrated the echo probe, registering it to the roadmap coordinate system.
- Validated techniques using cardiac MRI and 3-D echo data from eight volunteers.
Main Results:
- The model-based technique achieved higher accuracy (3.3 ± 1.1mm) compared to the echo-only technique (4.1 ± 2.2mm).
- Subjective assessments showed the model-based technique accurate to within 5mm in 60% of cases, versus 42% for the echo-only method.
- The model-based approach demonstrated superior robustness, especially outside the direct echo coverage area, and reduced computational cost.
Conclusions:
- Combining 3-D echo data with a respiratory motion model offers a more robust and accurate solution for roadmap motion correction in cardiac interventions.
- The model-based technique presents significant advantages in accuracy, robustness, and computational efficiency over echo-only methods.
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