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Motor and social development in 6-month-old children with congenital heart defects

Ragnhild Eek Brandlistuen1, Kim Stene-Larsen, Henrik Holmstrom

  • 1Department of Psychosomatics and Health Behavior, Norwegian Institute of Public Health, Post Box 4404,Nydalen, 0403 Oslo, Norway. ragnhild.eek.brandlistuen@fhi.no

The Journal of Pediatrics
|November 3, 2009
PubMed

Insights

Infants with severe congenital heart defects (CHD) and those with CHD and comorbidities show increased risks for motor impairments by 6 months of age. Comorbidities also elevate the likelihood of social development delays in these infants.

Area of Science:

  • Pediatric Cardiology
  • Developmental Pediatrics
  • Public Health

Background:

  • Congenital heart defects (CHD) are common birth anomalies.
  • Early developmental assessment is crucial for children with CHD.
  • The impact of CHD severity and comorbidities on infant development requires further investigation.

Purpose of the Study:

  • To evaluate developmental differences in infants with varying severities of congenital heart defect (CHD) compared to those without CHD at 6 months of age.

Main Methods:

  • A cohort study comparing 236 children with CHD to 61,032 controls from the Norwegian Mother and Child Cohort Study.
  • Children with CHD were categorized into mild, moderate, severe, and CHD with comorbidity groups.
  • Mothers reported on infant motor and social development at 6 months using the Mother and Child Questionnaire.

Main Results:

  • Severe CHD was associated with increased odds of gross motor impairment (OR 3.78) and fine motor impairment (OR 2.04).
  • CHD with comorbidity significantly increased the odds of gross motor impairment (OR 3.00), fine motor impairment (OR 5.47), and social impairment (OR 3.43).
  • Adjustments were made for confounders such as birth weight.

Conclusions:

  • Motor impairments are evident in infancy for infants with severe CHD and CHD with comorbidities.
  • Comorbidities in infants with CHD are linked to a higher risk of social development impairment.
Abstract

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