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Related Concept Videos

Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Vaccinations01:51

Vaccinations

Overview
Vaccines01:21

Vaccines

Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...
Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...

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Related Experiment Video

Updated: Jun 19, 2026

Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues
08:47

Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues

Published on: May 8, 2016

Transverse myelitis and vaccines: a multi-analysis.

N Agmon-Levin1, S Kivity, M Szyper-Kravitz

  • 1Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Israel.

Lupus
|November 3, 2009
PubMed
Summary

Vaccination can rarely trigger transverse myelitis, an autoimmune spinal cord injury. This review analyzed 37 cases, suggesting vaccine adjuvants may be a common trigger for this rare condition.

Area of Science:

  • Neurology
  • Immunology
  • Public Health

Background:

  • Transverse myelitis is a rare autoimmune disorder affecting the spinal cord.
  • Vaccination is a potential environmental trigger for autoimmune conditions.

Purpose of the Study:

  • To systematically review and analyze reported cases of transverse myelitis following vaccination.

Main Methods:

  • Systematic review of PubMed, EMBASE, and DynaMed databases.
  • Searched English-language journals published between 1970 and 2009.
  • Used keywords: transverse myelitis, myelitis, vaccines, post-vaccination, vaccination, autoimmunity.

Main Results:

  • Identified 37 reported cases of transverse myelitis associated with various vaccines.

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Related Experiment Videos

Last Updated: Jun 19, 2026

Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues
08:47

Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues

Published on: May 8, 2016

Modeling Multiple Sclerosis in the Two Sexes: MOG35-55-Induced Experimental Autoimmune Encephalomyelitis
05:44

Modeling Multiple Sclerosis in the Two Sexes: MOG35-55-Induced Experimental Autoimmune Encephalomyelitis

Published on: October 13, 2023

  • Temporal association ranged from days to months, occasionally years.
  • Affected individuals included infants, children, and adults.
  • Conclusions:

    • Vaccines, while crucial for public health, can rarely be linked to autoimmune phenomena like transverse myelitis.
    • The association of diverse vaccines with transverse myelitis suggests a common trigger, possibly vaccine adjuvants.