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Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery
Published on: November 5, 2019
Haemophilus influenzae serotype a meningitis.
Rubia Andreia Falleiros de Pádua1, Regiane Bertin de Lima Scodro, Luciana Dias Ghiraldi
1Department of Clinical Analyses, State University of Maringá, Maringá, Paraná, Brasil.
Annals of Clinical and Laboratory Science
|November 3, 2009
Summary
A case of Haemophilus influenzae serotype a meningitis occurred in Brazil post-Hib vaccine introduction. Continuous surveillance for invasive H. influenzae serotypes is crucial.
Area of Science:
- Microbiology
- Epidemiology
- Infectious Diseases
Background:
- The introduction of Haemophilus influenzae type b (Hib) conjugate vaccine significantly reduced Hib meningitis incidence.
- Non-typeable and non-b serotypes of H. influenzae remain causes of invasive disease.
Observation:
- A case of H. influenzae serotype a (Hia) meningitis was identified in Brazil.
- This occurred nearly ten years after the widespread implementation of the Hib conjugate vaccine.
Findings:
- H. influenzae serotype a can cause invasive meningitis even after successful Hib vaccination programs.
- This highlights the potential for serotype replacement in H. influenzae disease.
Implications:
- Continuous surveillance for all H. influenzae serotypes causing invasive diseases is essential.
- Further investigation into carriage rates and chemoprophylaxis for contacts is warranted to manage Hia meningitis risks.
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